Can THCV Actually Curb the Nibbles?
THCV has been dubbed “skinny pot” because of its supposed appetite suppressing and stimulating effects. But does it really work for weight loss? The results of scientific studies are very promising, especially for pure THCV and THCV in combination with CBD.
Read on for the latest research. If you want to try THCV for yourself, Rare Cannabinoid Company has an oil for you. This pioneering brand offers both a pure 500 mg THCV tincture and a one-to-one blend of THCV and CBD. Each batch is tested in the laboratory with results published online. See full product information below. First, however, it goes into the details about THCV and its potential benefits.
What is THCV?
THCV, short for tetrahydrocannabivarin, is a rare cannabinoid, which means that it occurs naturally in extremely small amounts in cannabis and hemp plants. While THC (tetrahydrocannabinol) is known to induce the nibbles, scientists are finding that THCV does the opposite.
“In rodent studies, THCV decreases appetite, increases satiety, and regulates energy metabolism. This makes it a clinically useful drug for weight loss and the treatment of obesity and type 2 diabetes,” according to Biomed Central’s Journal of Cannabis Research.
How does THCV reduce hunger?
Studies show that THCV and THCV with CBD can aid weight loss and promote wellbeing. The Rare Cannabinoid Company’s THCV tinctures can be seen here in Hawaii. (Courtesy photo of the Rare Cannabinoid Company)
Like other cannabinoids, THCV interacts with our endocannabinoid system (ECS). The ECS is a complex cell signaling system made up of endocannabinoids, receptors, and enzymes that can interact with its active chemical compounds, including cannabinoids such as THC, CBD, THCV, CBN, or CBG.
Experts are still learning how it works, but the ECS plays a role in regulating much of our mental and physical wellbeing, including appetite, mood, and sleep.
The ECS consists of two main types of receptors, CB1 and CB2. THC activates the CB1 receptor, which triggers the release of hunger-inducing hormones. THCV does the opposite, blocking the CB1 receptor and reducing hunger.
The appetite suppressing effects of blocking the CB1 receptor have been known for some time. However, drugs designed to block this receptor caused dire side effects. Thankfully, THCV doesn’t! The following studies explain this phenomenon:
Human studies of anti-obesity drugs vs. THCV
A pharmaceutical drug for obesity, rimonabant, was approved back in 2006 and worked in the same way as THCV by blocking the CB1 receptor. It was very effective in reducing weight and blood sugar levels in obese patients. However, it caused depression and was withdrawn from the market in 2008.
Experiments on human volunteers explain the differences between rimonabant and THCV.
In two separate studies, magnetic resonance imaging (MRI) was used to look at people’s neural responses while taking rimonabant or THCV.
The experiment on patients taking rimonabant found that the drug reduced the response to rewarding stimuli (delicious chocolate) while increasing the negative response to aversive sights and tastes (moldy strawberries). Scientists believe that blocking the “reward” or “pleasure” response to tasty foods was the likely cause of the patients’ depression. Not only did they crave less chocolate, but they also affected their ability to perceive pleasure, which is known to be a key symptom of major depression.
In contrast, the THCV study found that the volunteers’ reward function was not affected. It only increased the aversive stimulus that kept people from overeating without negatively affecting their mood.
Further studies show the potential use of THCV as a safer form of appetite control and also show that the rare cannabinoid alters connectivity between regions of the brain in such a way that “THCV may provide better control over food intake”.
Another related benefit of THCV is its potential to help with diabetes by regulating blood sugar and insulin levels. THCV appears to be more beneficial in type 2 diabetes while CBD is useful in type 1. “The combination of CBD and THCV can be beneficial in different types of diabetes mellitus,” concludes this animal study on THCV in diabetes.
Don’t let THC ruin the appetite suppressing effects of THCV!
Cannabis flower strains, including Doug’s Varin, Durban Poison, Tangie, and Jack the Ripper, all contain higher amounts of THCV (between 1 and 5%). However, these THCV-rich cannabis flowers are also high in THC, which will get you high and likely overwhelm the appetite control of the THCV.
This can be seen in an experiment on mice that contained three different forms of THCV: a pure herbal THCV, a THCV-style synthetic CB1 antagonist, and a THCV-rich cannabis extract. The pure THCV and the synthetic CB1 antagonist both suppressed food intake for 6-8 hours after ingestion and continuously in mice injected for four consecutive days. Both groups of mice lost a significant amount of weight and did not recover from additional food the day after their dosing was stopped.
However, mice given the THCV-rich cannabis extract neither ate less nor lost weight. It was believed that this was due to residual amounts of THC in the extract. To counteract the THC effect, these mice were given CBD (cannabidiol). Amazingly, it worked, and the mice fed less and lost weight.
According to the study, it appears that in order to lose weight, one has to take THCV without THC or at least counteract it with additional CBD.
Reach for the fridge again? Studies show that THCV has the potential to help people eat less. (Courtesy photo of the Rare Cannabinoid Company)
If you’d like to try THCV for yourself, Rare Cannabinoid Company is the first brand to offer pure THCV extract as well as a one-to-one blend of THCV and full-spectrum CBD made from rare Hawaiian hemp.
The amount of THCV is key
It’s also important to research the exact levels of THCV in different products. Some full-spectrum oils are said to contain high levels of a rare cannabinoid, but only contain traces of it.
The Rare Cannabinoid Company’s THCV single extract contains a whopping 500 mg of THCV. The only other ingredient is organic MCT coconut oil. Each spray contains 6.7 mg of THCV and there are 75 sprays per bottle. Milligrams are clearly listed on the packaging, and third-party lab reports are available online.
The Rare Cannabinoid Company’s full-spectrum CBD is made from hemp grown in Hawaii. Sunshine, tropical rain and rich red dirt combine to form a very special CBD. (Courtesy photo of the Rare Cannabinoid Company)
The brand’s “Ready Blend” option contains 250 mg THCV and 250 mg CBD. The Rare Cannabinoid Company’s full-spectrum CBD is made from hemp that is sun-grown in mineral-rich red dirt in Hawaii. Their THCV blend also contains organic MCT coconut oil and is lightly flavored with organic, food grade Italian lemon and wild orange oils.
Pharmacy-style approach to cannabinoids
This pioneering brand was created by the founders of Hawaii’s most popular CBD brand, Hawaiian Choice, to offer a pharmacy-like approach to mixing and combining cannabinoids for a personalized wellness experience. For example, CBN can be beneficial for sleep, CBG for fighting inflammation and bacteria, and CBC for mood and healthy skin.
In addition to THCV, Rare Cannabinoid Company sells tinctures made from CBN, CBC, CBG, full-spectrum Hawaiian CBD, and extra-potent 3000 mg CBD. (Courtesy photo of the Rare Cannabinoid Company)
The Rare Cannabinoid Company’s “Apothecary” line also offers 500 mg of single extracts of CBN, CBG and CBC as well as an extra high strength 3000 mg CBD (which comes with a glass container for precision dosing instead of a spray cap). The purified extracts come along with their Hawaiian CBD oil taken at 500 mg or 1000 mg full spectrum to get all the benefits of the entourage effect.
For those looking to combine rare cannabinoids with a broad spectrum oil instead of a full spectrum oil, all Hawaiian Choice products contain Hawaiian CBD with THC that has been filtered to laboratory-detectable levels (instead of below 0.3%).
Hawaiian Choice’s active CBD oil is a perfect match for the Rare Cannabinoid Company’s THCV as it contains three unique terpenes that increase energy and aid exercise and appetite control. It also tastes great thanks to infusions of organic and wild-picked Hawaiian pineapple, passion fruit, noni, hibiscus, and organic Big Island honey.
For those who don’t want to mix and match, the Rare Cannabinoid Company’s “Ready Blends” offer single blends of CBN, CBG and CBC, each with a full spectrum Hawaiian CBD. These blends are ideal for people who want a full off-the-shelf hemp supplement with the added benefits of high levels of rare cannabinoids.
Are you looking for other benefits of THCV?
Amazingly, each cannabinoid is believed to offer many different specific health and health benefits, both mentally and physically. In addition to the potential appetite suppressing effects of THCV, scientific studies have shown the following results:
You can learn more about rare cannabinoids and buy them at rarecannabinoidco.com
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