THC Isolate Defined – Every part You Want To Know


When it comes to any product other
than raw flowers, the cannabinoid in question needs to be extracted from the
plant matter and processed into a substance that’s pure, potent, and easily

If you’re trying to manufacture a
product with a very specific amount of any cannabinoid in it – medication for
example that would require accuracy down to the milligram, cosmetics,
supplements, and the like – you will need something called Isolate, in this
case – THC Isolate.

THC Isolate is the purest form of cannabigerol available on the market. As the name suggests, it’s THC isolated from every other compound. The final product is a white, powdery substance that’s over 99% pure. It can be added to everything including food, medications, cosmetics and more.

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What is Isolate?

the name implies, this THC Isolate is made by completely isolating the
cannabidiol from all the other plant matter and compounds. That means all other
cannabinoids, terpenes, flavonoids, and inactive compounds like plant waxes are
stripped from the extract, leaving only THC. The final product is a fine white
powder that has over 91% – 99% THC.

it’s odorless, tasteless, and highly concentrated, it’s the preferred extract
for use in the manufacture of many medical, wellness, and retail products. Its
purity means that 1 milligram of isolate equals exactly 1 milligram of THC,
whereas 1 milligram of less potent extract might have 0.5 milligrams of THC,
0.3 milligrams of CBD, and 0.2 combination of other terpenes and
compounds. This makes isolate very easy to use for specific dosing.

What is THC and what are the medical
benefits of this cannabinoid?

THC, or tetrahydrocannabinol, is the psychoactive
compound in cannabis that we all know and love. It’s also the most abundant cannabinoid
in most strains, not including hemp which will be higher in CBD or CBG. Although
THC is known for the high it causes, it also has numerous health and wellness

Since 1996 when California first legalized medical cannabis, one of its most common uses has always been to treat pain. Whether that pain stems from inflammation, headaches, injury, chemotherapy, cramps, or neuropathic pain, cannabis seems to be able to offer relief in every scenario. Due to the increase in opioid-related deaths, people are turning to cannabis as a way to safely treat their symptoms. And rightfully so, take a look at this study that examined the role of cannabinoids in pain management and discovered that a 1:1 ratio of THC:CBD can be extremely effective.

Some Amazing Benefits of Using THC

Anecdotal evidence will also tell you that THC is actually
one of the best remedies on earth for treating nausea, however, that’s
unfortunately not enough evidence for most people. But  there are some
legitimate studies that have echoed that sentiment which is promising for
anyone interested in using it. For example, this study looked at the effects of using THC to treat children
suffering from chemotherapy-induced nausea. According to the research,
“vomiting was completely prevented and the side effects observed were

Although the age of “reefer madness” led people to believe
that THC kills brain cells, it’s starting to appear like that couldn’t be
further from the truth. This study indicates that THC is actually a neuroprotectant
antioxidant. Something else extremely interesting was discovered in a 2014 study conducted at Harbor-UCLA Medical Center in Torrance,
California. Apparently, research found that the death rate following traumatic
brain injury was significantly lower in patients who tested positive for THC,
although this could also be due to a number of other factors.

Many will attest to the fact that THC can make them quite tired,
especially when using an indica strain with high concentrations. It’s also been
scientifically proven to be a useful sleep aid. Research shows that THC can “significantly decrease the time it takes
to fall asleep in physically healthy insomniacs.” A small 2008 study did mention that THC can reduce the amount of REM sleep
a patient gets which leads to less dreams, but that’s not the case for everyone
and a lack of dreaming doesn’t necessarily equate to poor sleep.

How is THC Isolate made?

To make isolate, the THC must be
extracted from the plant – and there are numerous ways to do this. The industry
gold standard and consumer favorite is CO2 extraction. The equipment is
industrial and very pricey, but this method results in a very pure final
product. A closed-loop system is used to cool CO2 to -56C, as the pressure
inside the chamber is hiked up to 75psi.

The CO2 becomes “supercritical” at this stage as it sits somewhere between a liquid and gaseous state. The CO2 is then passed through the closed chamber and, almost like a solvent, the cannabinoids and terpenes are extracted and remain intact. This process is called Supercritical CO2 Extraction. There’s also Subcritical CO2 Extraction which used cheaper equipment, lower pressure, and results in smaller yields.

Study Shows That THC Benefits Are Greater Than CBD’s

more cost-efficient but equally effective method is with an ethanol extraction
system. Ethanol extraction involves applying the solvent ethanol directly to
the hemp plant in order to extract the cannabinoids.
Ethanol extraction has gotten a bad reputation as being unsafe, but that’s
simply incorrect. Ethanol extraction is actually an FDA-approved method
of extraction compounds from various plants in order to make food and

is one issue with ethanol extraction, however. Certain compounds easily
co-extract with ethanol, and the one of concern here is chlorophyll.
Chlorophyll is a molecule that absorbs sunlight and converts it into plant
energy. It also gives plants their green color. When using ethanol extraction,
the chlorophyll may need to be stripped away in a separate process.

What is THC Isolate Used For?

can be used to make anything that has THC in it – edibles, topicals,
tinctures, softgels, nasal sprays, various pharmaceuticals, and the list goes
on. Anything that requires accurate dosing and very specific measurments will
benefit from isolate.

even better if the isolate is manufactured in a GMP-certified facility GMP
stands for Good Manufacturing Practice and it’s already a requirement in
Europe, India, and many other countries/continents that all medications,
supplements, and cosmetics must be GMP-certified.

while the North American market is currently an unregulated free-for-all, this
is expected to change over the next few years. GMP is the way of the future
when it comes to the medical cannabis and hemp industries.

Final Thoughts

As you can see, there are many valuable uses for high-quality distillate. If you would like to purchase some, we have partnered with some leading companies who manufacture EU GMP-certified THC Isolate.

For more articles like this one, make sure to subscribe to the CBD Business Weekly Newsletter, your source for all things cannabis and hemp related.

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Beth Edmonds