PHARMA

Will authorized artificial cannabinoids take over the hashish trade?

will-authorized-artificial-cannabinoids-take-over-the-hashish-trade

We live in a world of plastics. Most of our clothing is no longer made of cotton, but a mixture of plastics. Much of our food is made up of chemicals that can hardly be pronounced. And now cannabis, our favorite smoke and recreational medicine Pastime, could soon be replaced by legal synthetic cannabinoids.

It's a world of plastics

My mother worked with a man who had a good opportunity to get coach bags. For anyone unfamiliar with the brand, Coach makes high quality leather bags that come at a nice high price point. My mother bought tons of them, gave them away as gifts, and used a different one every day. They weren't real, of course, though I don't remember how she found that out. They were fakes. Products that looked almost exactly the same, felt almost exactly the same, but were actually made from completely different materials and of lower quality overall. My mother was very unhappy when she realized what was going on and never spoke to her co-worker again who had bamboozled her, but buying synthetic products is pretty normal and often most people never know what they have. t the real thing.

Aren't synthetic cannabinoids already a big deal?

Yes! Firmly! If you read the internet you might get a little confused. Every time words like "spice" and "k2" are uttered in relation to cannabis, it is referring to synthetic cannabinoids. So what's the difference between these synthetic cannabinoids and the legal synthetic cannabinoids that the biotech industry is trying to manufacture and bring to market quickly? Good question. While big biotech companies have the money and the ability to make various inventions, technically they don't produce anything that is terribly far from the illegal version that people are constantly warned about with terror stories of a few people going on for years died. In the cited article it should be noted that most of the deaths were not even due to synthetic cannabis, but rather from a rat poison contaminant. Of course, these stories are somehow all forgotten or brushed aside when the plastics being talked about come from companies that can sell their products overboard and have them taxed by the government. Funny how that works, isn't it? I suppose one could argue that it is regulated or unregulated and that one is more dangerous than the other, the lack of relevant deaths from the unregulated version (no matter how much the few that occur are made public, we remember of what it really is to have an epidemic of overdose), and the standard story of knocking down the one who doesn't bring in the state tax dollars while promoting the one that does – and makes the big biotech companies billions – , is not unfamiliar to history at all. No, synthetic cannabis is far from new. I smoked Mr. Nice Guy in Tel Aviv 10 years ago and people on the street back then said it was all synthetic. Now, with a massive 180 degrees that are constantly being warned about, the new is now being pushed forward by large biotech companies.

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synthetic cannabinoids

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The new world of cannabis plastics

The production of synthetic cannabis appears to be twofold. Sometimes it's just about making an alternate version (which can be legally patented) and sometimes it's about producing a substance on a large scale that is only found in tiny, tiny amounts. Such as CBG or cannabigerol, a cannabinoid that only makes up about 1% of a cannabis plant at the time of harvest and that – similar to CBD – has been linked to pain management as an anti-inflammatory agent, neurodegenerative diseases and glaucoma. In fact, in partnership with manufacturer Albany Molecular Research, Willow Biosciences has produced a large scale production of the cannabinoid, which, like CBD, has not been associated with psychoactive effects, making it a good addition to the medical cannabis family.

Willow is a Canadian company based in Calgary, but it already has a lot of competition. US-based Biomedican Inc. of Fremont, Calif., Is giving Willow a run for their money, claiming they already have a CBG strain that is ready for mass production. Two other companies, Demetrix and Amyris, also want to deal specifically with the CBG game. In a statement that was incredibly and deeply misinterpreted to me, Headset, which appears to be tracking cannabis trends, made the statement that cannabinoids in the market today are mostly derived from plants, especially in products like vape pens, but those synthetic versions should be coming soon. That thought would have a lot more meaning if we weren't constantly told to stay away from "spices" and "herbs", which are synthetic cannabinoids on the black market. In fact, most of the vape pens sold in a place like California, which has the largest legal cannabis market, are fake, and that means synthetic cannabinoids !! Whoever made a statement at Headset that was picked up by Inquirer just had to talk about the legal market, and the thing about cannabis is that if you just look at the legal market, you are missing so much, just looking at what's going on. So much so that we talk about legal synthetic cannabinoids as if they had just come out if the majority of us who vape pens or smoke "artificial weeds" have been using them for years … and generally without incident.

What do you make plastics from?

Pretty much anything that can be isolated from the cannabis plant and has some value. CBN, CBG, THC-A, THC-V, Delta-8 THC … This is probably a good time to remember Marinol. While this whole discussion of plastics continues, it's easy to forget that along with all of the black market plastics that are being warned about, there is Marinol. Marinol, also known as Dronabinol, is a fully synthetic cannabis drug that has been around since 1986, and which is being manufactured by several pharmaceutical companies at the time. So it is entirely possible that pharmaceutical versions of cannabis, not even a pharmaceutical new idea, have not yet tainted the industry for which they were intended.

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Dronabinol

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Why plastics?

This should be more obvious than it is likely to be to most people. If the majority of the vape pens out there are counterfeit, and if the mass production of "artificial weeds" is cheaper (probably wouldn't have been possible if it was more expensive as criminal organizations generally don't look for counterfeit higher prices) than it it is understood that in the case of cannabis, counterfeiting is cheaper. This means that extracting real cannabinoids will be a much more expensive and difficult process than making plastics, which can then be mass-produced at a lower cost.

If you take a step back it becomes almost silly. Growing cannabis is one of the easiest and very cheapest things to do. Just remember that in any legal place a person can generally grow their own plants. But once it becomes a regulated market and prices go up, it's no longer cheap, especially when you factor in pharmacy prices and massive taxes. Synthetics, on the other hand, make it cheaper again – and bring it back to where it would likely be offered on the black market at a price (although I can't confirm this as there is currently no comparable price). . But it also does something else … Plants cannot be patented, at least not in their natural form. However, modified or synthetic versions can be. While the cannabis game has been difficult to control for pharmaceutical companies, creating a non-herbal version gives our biotech and pharmaceutical compatriots the opportunity to develop a substance that can be patented.

What to expect

The general expectation is that the biotech and pharmaceutical industries will do whatever it takes to cooperate with the medical marijuana and general legal cannabis industries. Whether it will work or not is a different story. Sometimes drug companies don't have the allure they want. In this case, everyone would already be using Marinol and Sativex, and they are not. The problem with cannabis with large pharmaceuticals is that cannabis is not a medicine unless it is. If people are never interested in these new medical advances, the old rules remain and people keep smoking the plant. If big drug companies can produce a product at the right price that is sufficiently accessible and does the job, it could be a whole different story. In this particular case, it's an interesting battle for the market and it's hard to say how it will go on. In the case of cannabis, it should be noted that we do not need any of this technically. The more production goes into cannabis, the higher the cost and the more synthetic answers need to be found.

Take that away

It looks like the legal medical cannabis (and possibly recreational) market will soon be flooded with legal synthetic cannabinoids. What does that really mean? Well, that's up to all of you. If you want your plant to be a plant then smoke your plant and nature wins. If you're cool with the synthetic version go out there and use it. The ability of the synthetic market to do well is largely related to the ability of biotech companies and governments to convince their employees that plastics are a better answer.

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Beth Edmonds